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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-8-60-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-8-8-7</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Toxic Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Lead Exposure: Inappropriate Screening Practices?</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>08</month>
<year>1994</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>06</month>
<year>2016</year>
</pub-date>
<volume>8</volume>
<issue>8</issue>
<fpage>60</fpage>
<lpage>62</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1994 The Author(s)</copyright-statement>
<copyright-year>1994</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1001/archpedi.1994.02170070026004" vol="148" page="688">
<article-title>Lead screening among high-risk urban children. Are the 1991 Centers for Disease Control and Prevention guidelines feasible?</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>Physician screening practices at a hospital-based, university-affiliated pediatric primary care center serving an urban high-risk population in Rochester, NY were evaluated to determine the feasibility of the 1991 Centers for Disease Control guidelines.</p>
</abstract>
<kwd-group>
<kwd>Lead Toxic Effects</kwd>
<kwd>Blood Lead Levels</kwd>
<kwd>Venipuncture</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Physician screening practices at a hospital-based, university-affiliated pediatric primary care center serving an urban high-risk population in Rochester, NY were evaluated to determine the feasibility of the 1991 Centers for Disease Control guidelines. Among 632 children aged 9 to 25 months who attended the center between 1989 and 1991, screening was deficient in 55%, 34%, and 29% at ages 9-13 months, 14-19 months, and 20-25 months, respectively. Many high-risk children living in houses built before 1950, including those making well-child visits, were not appropriately screened for lead toxic effects, and opportunities for testing were frequently missed. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<disp-quote>
<p>COMMENT. The authors believe that the new CDC guidelines for biannual screening and retesting can be achieved with a modest increase in tests, if sick visits are also utilized for retesting. Proper cleansing of the fingertip or alternatively, venipuncture should decrease the proportion of false-positive results and reduce the need for additional visits. At this urban PC Center, 30% of the screened high-risk children had lead levels of 10 mcg/dL or higher, now considered to be toxic. In contrast, only 4.7% of children screened from a suburban, middle class private practice in Cherry Hill, NJ, were found to have elevated blood lead levels, and no child had a level of 25 mcg/dL or higher requiring treatment. [<xref ref-type="bibr" rid="CIT0002">2</xref>]</p>
<p><bold>Who Bears the Burden?</bold> Wical BS, of the Departments of Neurology and Pediatrics, University of New Mexico, Albuquerque, addresses the dilemmas and burdens of blood lead testing of 22 million children in the US from 6 to 72 months of age [<xref ref-type="bibr" rid="CIT0003">3</xref>]. In Milwaukee, private physicians play a major role in lead poisoning screening and case identification. In 1992, the number of cases of poisoning identified (BPb 25 mcg/dL or higher) in the private sector increased by over 600% in a 2 year period, a higher number than in public centers. Physicians voluntarily changed their practice patterns in accordance with 1991 CDC recommendations, partly as a result of physician education by the Milwaukee Health Department and the Children&#x2019;s Hospital of Wisconsin. [<xref ref-type="bibr" rid="CIT0004">4</xref>]</p>
<p><bold>The Child Neurologist&#x2019;s Role.</bold> Pediatric neurologists may need to take some responsibility in the blood lead screening of their patients, particularly those in high-risk categories. No child is exempt from risk, however; one infant, a pediatric surgeon&#x2019;s child, living in a high-rise co-op apartment, the first to be built in Chicago in 1924, and another, a house master&#x2019;s child at a renown boarding school in Massachusetts, were exposed to lead containing paint in the homes. Blood lead levels, in both cases prompted by the mothers and found to be elevated, responded to a temporary change of residence and lead abatement measures.</p>
<p><bold>Declining Lead Levels.</bold> Despite the dramatic overall decrease in blood lead levels in the US population in recent years to 2.8 mcg/dL, national estimates for children 1 to 5 years of age show that 8.9%, or 1.7 million children, have BPb levels of 10 mcg/dL or greater, high enough to be of concern [<xref ref-type="bibr" rid="CIT0005">5</xref>]. Pirkle JL, Brody DJ et al, commenting on the decline in blood lead levels in the US, attribute the fall to the removal of lead from gasoline and soldered cans. Lead in paint, dust and soil needs to be addressed before the decline can continue, especially in children in low income, urban areas [<xref ref-type="bibr" rid="CIT0006">6</xref>]. Goldman LR and Carra J, from the Office of Prevention, Pesticides, and Toxic Substances, US Environmental Protection Agency, Washington, DC, emphasize the need for both targeted screening efforts and improvements in screening methods in high-risk children. [<xref ref-type="bibr" rid="CIT0007">7</xref>]</p>
<p><bold>Public Lead Awareness and Responsibility.</bold> Since current compliance with CDC recommended guidelines for blood lead screening is not universally appropriate, an increased public and parent awareness of the hazards and the symptoms and signs of lead poisoning, especially in children, should be encouraged. [<xref ref-type="bibr" rid="CIT0008">8</xref>]</p>
</disp-quote>
</body>
<back>
<ref-list>
<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Campbell</surname>
<given-names>JR</given-names>
</name>
<name>
<surname>McConnochie</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Weitzman</surname>
<given-names>M</given-names>
</name>
</person-group>
<article-title>Lead screening among high-risk urban children. Are the 1991 Centers for Disease Control and Prevention guidelines feasible?</article-title>
<source>Arch Pediatr Adolesc Med</source>
<year>1994</year>
<month>Jul</month>
<volume>148</volume>
<issue>7</issue>
<fpage>688</fpage>
<lpage>693</lpage>
<pub-id pub-id-type="doi">10.1001/archpedi.1994.02170070026004</pub-id>
<pub-id pub-id-type="pmid">8019621</pub-id>
</element-citation>
</ref>
<ref id="CIT0002">
<label>2</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Taubman</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Wiley</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Henretig</surname>
<given-names>F</given-names>
</name>
</person-group>
<article-title>Prevalence of elevated blood lead levels in a suburban middle class private practice</article-title>
<source>Arch Pediatr Adolesc Med</source>
<year>1994</year>
<month>Jul</month>
<volume>148</volume>
<issue>7</issue>
<fpage>757</fpage>
<lpage>760</lpage>
<pub-id pub-id-type="doi">10.1001/archpedi.1994.02170070095017</pub-id>
<pub-id pub-id-type="pmid">8019633</pub-id>
</element-citation>
</ref>
<ref id="CIT0003">
<label>3</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Wical</surname>
<given-names>BS</given-names>
</name>
</person-group>
<article-title>Lead: who bears the burden?</article-title>
<source>Arch Pediatr Adolesc Med</source>
<year>1994</year>
<month>Jul</month>
<volume>148</volume>
<issue>7</issue>
<fpage>760</fpage>
<lpage>761</lpage>
<pub-id pub-id-type="doi">10.1001/archpedi.1994.02170070098019</pub-id>
<pub-id pub-id-type="pmid">8019634</pub-id>
</element-citation>
</ref>
<ref id="CIT0004">
<label>4</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Schlenker</surname>
<given-names>TL</given-names>
</name>
<name>
<surname>Fritz</surname>
<given-names>CJ</given-names>
</name>
<name>
<surname>Murphy</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Shepeard</surname>
<given-names>S</given-names>
</name>
</person-group>
<article-title>Feasibility and effectiveness of screening for childhood lead poisoning in private medical practice</article-title>
<source>Arch Pediatr Adolesc Med</source>
<year>1994</year>
<month>Jul</month>
<volume>148</volume>
<issue>7</issue>
<fpage>761</fpage>
<lpage>764</lpage>
<pub-id pub-id-type="doi">10.1001/archpedi.1994.02170070099020</pub-id>
<pub-id pub-id-type="pmid">8019635</pub-id>
</element-citation>
</ref>
<ref id="CIT0005">
<label>5</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Brody</surname>
<given-names>DJ</given-names>
</name>
<name>
<surname>Pirkle</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Kramer</surname>
<given-names>RA</given-names>
</name>
<name>
<surname>Flegal</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Matte</surname>
<given-names>TD</given-names>
</name>
<name>
<surname>Gunter</surname>
<given-names>EW</given-names>
</name>
<etal/>
</person-group>
<article-title>Blood lead levels in the US population. Phase 1 of the Third National Health and Nutrition Examination Survey (NHANES III, 1988 to 1991)</article-title>
<source>JAMA</source>
<year>1994</year>
<month>Jul</month>
<day>27</day>
<volume>272</volume>
<issue>4</issue>
<fpage>277</fpage>
<lpage>283</lpage>
<pub-id pub-id-type="doi">10.1001/jama.272.4.277</pub-id>
<pub-id pub-id-type="pmid">8028140</pub-id>
</element-citation>
</ref>
<ref id="CIT0006">
<label>6</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Pirkle</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Brody</surname>
<given-names>DJ</given-names>
</name>
<name>
<surname>Gunter</surname>
<given-names>EW</given-names>
</name>
<name>
<surname>Kramer</surname>
<given-names>RA</given-names>
</name>
<name>
<surname>Paschal</surname>
<given-names>DC</given-names>
</name>
<name>
<surname>Flegal</surname>
<given-names>KM</given-names>
</name>
<etal/>
</person-group>
<article-title>The decline in blood lead levels in the United States. The National Health and Nutrition Examination Surveys (NHANES)</article-title>
<source>JAMA</source>
<year>1994</year>
<month>Jul</month>
<day>27</day>
<volume>272</volume>
<issue>4</issue>
<fpage>284</fpage>
<lpage>291</lpage>
<pub-id pub-id-type="doi">10.1001/jama.272.4.284</pub-id>
<pub-id pub-id-type="pmid">8028141</pub-id>
</element-citation>
</ref>
<ref id="CIT0007">
<label>7</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Goldman</surname>
<given-names>LR</given-names>
</name>
<name>
<surname>Carra</surname>
<given-names>J</given-names>
</name>
</person-group>
<article-title>Childhood lead poisoning in 1994</article-title>
<source>JAMA</source>
<year>1994</year>
<month>Jul</month>
<day>27</day>
<volume>272</volume>
<issue>4</issue>
<fpage>315</fpage>
<lpage>316</lpage>
<pub-id pub-id-type="doi">10.1001/jama.1994.03520040077045</pub-id>
<pub-id pub-id-type="pmid">8028147</pub-id>
</element-citation>
</ref>
<ref id="CIT0008">
<label>8</label>
<element-citation publication-type="book">
<person-group person-group-type="author">
<name>
<surname>Millichap</surname>
<given-names>JG</given-names>
</name>
</person-group>
<article-title>Environmental Poisons in Our Food</article-title>
<year>1993</year>
<publisher-loc>Chicago</publisher-loc>
<publisher-name>PNB Publishers</publisher-name>
</element-citation>
</ref>
</ref-list>
</back>
</article>