1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-8-51-a 10.15844/pedneurbriefs-8-7-4 Antiepileptic Therapies Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Propofol Anesthesia-Induced Seizures http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 07 1994 01 06 2016 8 7 51 51 Copyright: © 1994 The Author(s) 1994 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Propofol, seizures and generalized paroxysmal fast activity in the EEG

A case of a healthy young man who developed seizures and generalized paroxysmal fast activity in the EEG following use of propofol for anesthesia in minor surgery is reported from the Department of Neurology, University of South Alabama, Mobile, AL.

 Propofol Anesthesia Divalproex Myoclonic Jerking

A case of a healthy young man who developed seizures and generalized paroxysmal fast activity in the EEG following use of propofol for anesthesia in minor surgery is reported from the Department of Neurology, University of South Alabama, Mobile, AL. Myoclonic jerking and obtundation developed shortly after anesthesia and a generalized seizure associated with EEG paroxysmal fast activity and controlled with divalproex occurred the following day. [1]

COMMENT. Propofol anesthesia has been associated with seizures, myoclonic jerking and opisthotonic posturing. Spikes, polyspikes and spike wave complexes in the EEG have also been reported. The fast activity in the EEG in the above case was considered to be epileptiform, resolving after short-term anticonvulsant therapy.

 Nowack WJ Jordan R Propofol, seizures and generalized paroxysmal fast activity in the EEG Clin Electroencephalogr 1994 Jul 25 3 110 114 10.1177/155005949402500308 8088014