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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-8-55</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-8-7-11</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Attention Deficit and Learning Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>MRI Changes in Dyslexia: A Reappraisal</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>07</month>
<year>1994</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>06</month>
<year>2016</year>
</pub-date>
<volume>8</volume>
<issue>7</issue>
<fpage>55</fpage>
<lpage>56</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1994 The Author(s)</copyright-statement>
<copyright-year>1994</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1002/ana.410350615" vol="35" page="732">
<article-title>Brain morphology in normal and dyslexic children: the influence of sex and age</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>The convolutional surface area of the planum temporale, temporal lobe volume, and brain volume were compared by MRI in 17 dyslexic children (7 girls) and 14 controls (7 girls) at Yale University School of Medicine, New Haven.</p>
</abstract>
<kwd-group>
<kwd>Dyslexia</kwd>
<kwd>Brain Morphology</kwd>
<kwd>Parahippocampal Gyrus</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>The convolutional surface area of the planum temporale, temporal lobe volume, and brain volume were compared by MRI in 17 dyslexic children (7 girls) and 14 controls (7 girls) at Yale University School of Medicine, New Haven. All measurements were significantly larger in boys. Age was directly correlated with brain region volumes. Analyses that controlled for age and overall brain size failed to confirm smaller left hemisphere structures previously reported in dyslexics. The authors suggest that differences in sex, age, handedness, and definition of dyslexia as well as methods of measurement of the planum temporale may explain apparent discrepancies in results of neuroimaging studies in dyslexic subjects. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<disp-quote>
<p>COMMENT. This important study casts doubt on the significance of reports of differences in brain morphology in children with dyslexia and other learning disabilities. It should be noted in the Massachusetts General Hospital report of corpus callosal changes in ADDH children, a smaller splenium was unrelated to the age of the children, (see above).</p>
<p>Age-related changes in the brains of patients with Down&#x2019;s syndrome measured by MRI analyses are reported from the University of California, Irvine. [<xref ref-type="bibr" rid="CIT0002">2</xref>]</p>
<p>The changing conception of mental retardation and the implications of the new 1992 American Association on Mental Retardation&#x2019;s (AAMR) definition and classification are outlined by psychologists, psychiatrists, pediatricians, pediatric neurologists, and educators [<xref ref-type="bibr" rid="CIT0003">3</xref>]. The 1992 System shifts the diagnostic effort from estimating the level of an individual&#x2019;s deficiency (mild, moderate, severe) to the intensities of needed supports (intermittent, limited, extensive, pervasive). Professional/clinical judgement is emphasized in assessments, and the terms educable and trainable are considered inappropriate. Special education services and supports are based on functioning level rather than IQ-derived levels of retardation. An etiological classification of biological or psychosocial categories is modified and expanded to a multifactorial approach which includes intergenerational and environmental factors. Research studies based on the new paradigm will emphasize environments and supports, quality of life, and a greater precision in definition.</p>
</disp-quote>
</body>
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