GABA Synthesis and Pyridoxine Seizures

Authors

  • J Gordon Millichap Northwestern University Feinberg School of Medicine

DOI:

https://doi.org/10.15844/pedneurbriefs-8-6-6

Keywords:

Pyridoxal-5-Phosphate, Glutamic Acid Decarboxylase, Epileptiform Activity

Abstract

A reduction in pyridoxal-5-phosphate (PLP) dependent enzyme, glutamic acid decarboxylase (GAD),which synthesizes GABA, is reported in a 3 month-old infant with seizures responsive to pyridoxine treated at University of California, Davis.

Published

1994-06-01

Issue

Section

Seizure Disorders