1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-8-94-b 10.15844/pedneurbriefs-8-12-10 Seizure Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Focal Spect Lesions and Infantile Spasms http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 12 1994 01 06 2016 8 12 94 95 Copyright: © 1994 The Author(s) 1994 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Infantile spasms: localized cerebral lesions on SPECT

Seven of 10 patients with infantile spasms examined by SPECT at Tokushima University School of Medicine, Japan, showed localized cerebral hypoperfusion in the temporal lobes.

 Temporal Lobes Focal Abnormalities Infantile Spasms

Seven of 10 patients with infantile spasms examined by SPECT at Tokushima University School of Medicine, Japan, showed localized cerebral hypoperfusion in the temporal lobes. EEGs near time of SPECT showed corresponding focal abnormalities in 5. The MRI was less revealing, with confirmation of localized lesions in only 3. [1]

COMMENT. Infantile spasms may be associated with focal temporal lobe hypoperfusion on SPECT despite normal MRI.

PET studies of infantile spasms have also shown focal abnormalities when MRI was normal. [2]

 Miyazaki M Hashimoto T Fujii E Tayama M Kuroda Y Infantile spasms: localized cerebral lesions on SPECT Epilepsia 1994 Sep-Oct 35 5 988 992 10.1111/j.1528-1157.1994.tb02543.x 7925170 Chugani HT Progress in Pediatric Neurology Vol II 1994 35