1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-8-06-a 10.15844/pedneurbriefs-8-1-10 Vascular Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Outcome of Neonatal Stroke http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 01 1994 01 06 2016 8 1 6 6 Copyright: © 1994 The Author(s) 1994 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Results of parenchymal and angiographic magnetic resonance imaging and neuropsychological testing of children after stroke as neonates

Evaluations, including MRI, MR angiography, and neuropsychological tests, at 1.5-8.4 years, of 8 infants after neonatal stroke involving the middle cerebral artery are reported from the University of Heidelberg, Mannheim, Germany.

 Neonatal Stroke Middle Cerebral Artery Magnetic Resonance Angiography

Evaluations, including MRI, MR angiography, and neuropsychological tests, at 1.5-8.4 years, of 8 infants after neonatal stroke involving the middle cerebral artery are reported from the University of Heidelberg, Mannheim, Germany. Seven had mental and motor retardation and hemiparesis and 4 had epilepsy. Major deficits in cognitive function were found in 4 older children. One patient with normal development showed only a localized temporal lobe lesion on MRI and unremarkable MRA. Children with marked disorders of motor and cognitive development had defects of temporo-parietal lobes, basal ganglia, thalamus and internal capsule on MRI and recanalization of the middle cerebral artery shown on MRA. Those without recanalization had a poorer prognosis. [1]

COMMENT. Magnetic resonance angiography (MRA) images intracranial blood vessels without necessity for invasive contrast media. Children with neonatal stroke, seizures, and abnormalities shown on MRA have severe cognitive delays and the least favorable prognosis on long-term follow up.

 Koelfen W Freund M Konig S Varnholt V Rohr H Schultze C Results of parenchymal and angiographic magnetic resonance imaging and neuropsychological testing of children after stroke as neonates Eur J Pediatr 1993 Dec 152 12 1030 1035 10.1007/BF01957231 8131805