1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-7-54-a 10.15844/pedneurbriefs-7-7-8 Status Epilepticus Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Serum Cortisol and Prognosis of Status Epilepticus http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 07 1993 01 07 2016 7 7 54 54 Copyright: © 1993 The Author(s) 1993 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Serum cortisol and cerebrospinal fluid beta-endorphins in status epilepticus. Their possible relation to prognosis

The relation of serum Cortisol and CSF B-endorphin levels to the prognosis of status epilepticus was evaluated in 27 adults treated in the Comprehensive Epilepsy Program of the Medical College of Virginia, Richmond, VA.

 Serum Cortisol Status Epilepticus Blood Cortisol Level

The relation of serum Cortisol and CSF B-endorphin levels to the prognosis of status epilepticus was evaluated in 27 adults treated in the Comprehensive Epilepsy Program of the Medical College of Virginia, Richmond, VA. Poor prognosis was defined as death or severe neurologic or medical complications during or within one week after status epilepticus of more than 30 minutes. Blood Cortisol levels were significantly elevated in patients with a poor outcome. CSF B-endorphins were significantly increased but did not correlate with prognosis. [1]

COMMENT. Serum Cortisol determinations within 12 hours after control of status epilepticus may predict prognosis. The authors also propose that the rise in Cortisol levels may contribute to the pathology of status epilepticus.

 Calabrese VP Gruemer HD Tripathi HL Dewey W Fortner CA DeLorenzo RJ Serum cortisol and cerebrospinal fluid beta-endorphins in status epilepticus. Their possible relation to prognosis Arch Neurol 1993 Jul 50 7 689 693 10.1001/archneur.1993.00540070009006 8323469