1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-7-55-a 10.15844/pedneurbriefs-7-7-10 Vascular Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Moyamoya Disease and Hemiplegic Migraine http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 07 1993 01 07 2016 7 7 55 55 Copyright: © 1993 The Author(s) 1993 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Hemiplegic migraine and moyamoya disease

A 6-year-old girl presenting with a 6-month history of classical familial migraine, complicated by transitory hemiparesis and moyamoya disease diagnosed by MRI, is reported from the Kaiser Permanente Medical Center, Hayward, CA.

 Moyamoya Disease Hemiplegic Migraine Neurologic Deficits

A 6-year-old girl presenting with a 6-month history of classical familial migraine, complicated by transitory hemiparesis and moyamoya disease diagnosed by MRI, is reported from the Kaiser Permanente Medical Center, Hayward, CA. Headaches occurred each week and were associated with nausea, vomiting, and photophobia. She awoke on 3 occasions with right-sided weakness, numbness, and garbled speech. All symptoms resolved after two hours of sleep. Neurologic exam was normal between attacks. MRI showed bilateral occlusion of the carotid arteries and increased vascularity of collateral vessels in the basal ganglia, consistent with moyamoya. [1]

COMMENT. Children with a diagnosis of hemiplegic migraine may have a vascular malformation or moyamoya disease as the underlying pathology. The clinical course depends on the rapidity and extent of vascular occlusion and the ability to develop a collateral circulation. Early diagnosis and surgical revascularization have been advocated because of the risk of permanent neurologic deficits. (See Ped Neur Briefs July 1987, and Progress in Pediatric Neurology, Chicago, PNB Publ, 1991, pp389-391).

 Bernstein AL Hemiplegic migraine and moyamoya disease Am J Dis Child 1993 Jul 147 7 718 719 10.1001/archpedi.1993.02160310020008 8322737