1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-7-04 10.15844/pedneurbriefs-7-1-6 Seizure Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Neonatal Electrographic Seizures http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 01 1993 01 07 2016 7 1 4 4 Copyright: © 1993 The Author(s) 1993 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae

Preterm and full-term neonates with electrographically confirmed seizures were compared at the University of Pittsburgh School of Medicine. The incidence of seizures for all neonates admitted to a neonatal ICU was 2.3%.

 Electrographically Clinical Seizures Intraventricular Hemorrhage

Preterm and full-term neonates with electrographically confirmed seizures were compared at the University of Pittsburgh School of Medicine. The incidence of seizures for all neonates admitted to a neonatal ICU was 2.3%. Of 92 neonates with EEG-confirmed seizures seen over a 4 year period, 62 were preterm and 30 were full-term. Seizure frequency of preterm 30 wk neonates was 3.9% and significantly higher than that of older neonates. Clinical seizures were noted in 45% of preterm and 53% of full-term neonates. Seizures were subtle in 71% and 68%, respectively. Ischemic brain lesions were diagnosed in 39% of preterm compared to 77% of full-term neonates. Intraventricular hemorrhage occurred in 45% of preterm and only in 3% of full-term neonates. Mortality was higher in the preterm than in the term populations. [1]

COMMENT. More than 50% of this cohort had only electrographic expression of seizures. A later onset of seizures in preterm neonates suggests adverse medical complications after birth. One cannot always rely on simultaneous electrographic confirmation of seizures since 16% of patients exhibit electroclinical dissociation.

 Scher MS Aso K Beggarly ME Hamid MY Steppe DA Painter MJ Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae Pediatrics 1993 Jan 91 1 128 34 8416475