1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-6-68-a 10.15844/pedneurbriefs-6-9-4 Vascular Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Neonatal Cerebral Venous Thrombosis http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 09 1992 01 07 2016 6 9 68 68 Copyright: © 1992 The Author(s) 1992 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Neonatal idiopathic cerebral venous thrombosis: an unrecognized cause of transient seizures or lethargy

The clinical presentation and management of 7 neonates with idiopathic cerebral venous thrombosis (CVT) are reported from the Floating Hospital for Infants and Children, New England Medical Center Hospitals, Tufts University School of Medicine, Boston, MA.

 Cerebral Venous Thrombosis Neurological Evaluation Sinuses

The clinical presentation and management of 7 neonates with idiopathic cerebral venous thrombosis (CVT) are reported from the Floating Hospital for Infants and Children, New England Medical Center Hospitals, Tufts University School of Medicine, Boston, MA. Unexplained seizures in 3 infants and unexplained lethargy in 4 led to neurological evaluation and the diagnosis of CVT. Follow-up neurological evaluation through 6 months of age showed normal development. Conventional magnetic resonance images indicated more extensive thrombosis than was suggested by cranial CT. MR phase imaging confirmed thrombosis and established absence of blood flow in cerebral veins or sinuses. No infant received treatment with anticoagulants. [1]

COMMENT. Cerebral venous thrombosis may explain transient neonatal seizures or lethargy in newborn infants and may be diagnosed by MR and MR phase imaging.

 Rivkin MJ Anderson ML Kaye EM Neonatal idiopathic cerebral venous thrombosis: an unrecognized cause of transient seizures or lethargy Ann Neurol 1992 Jul 32 1 51 56 10.1002/ana.410320109 1642472