1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-6-62 10.15844/pedneurbriefs-6-8-8 Seizure Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Occipital Lobe Seizures and Celiac Disease http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 08 1992 01 07 2016 6 8 62 62 Copyright: © 1992 The Author(s) 1992 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Occipital lobe seizures related to clinically asymptomatic celiac disease in adulthood

The electroclinical ictal findings of 4 epileptic patients with clinically asymptomatic celiac disease are reported from the University of Bologna, Italy.

 Occipital Lobe Celiac Disease Cerebral Calcification

The electroclinical ictal findings of 4 epileptic patients with clinically asymptomatic celiac disease are reported from the University of Bologna, Italy. All patients had paroxysmal visual manifestations and EEG seizure discharges arising from the occipital lobe. CT in 2 patients showed occipital calcifications. A gluten-free diet was not beneficial and polytherapy with antiepileptic drugs aggravated the seizures in 3 cases. Epilepsy and evidence of steatorrhea and growth failure were present in early childhood. The diagnosis of celiac disease was made by tests for serum folate level, a d-zylose absorption test, anti-gliadin antibody test and jejunal biopsy which showed villous atrophy. [1]

COMMENT. The same authors had investigated 10 patients with epilepsy and occipital cerebral calcification and had found evidence of celiac disease in 6. All patients with epilepsy and posterior cerebral calcification should be investigated for possible celiac disease. [2]

 Ambrosetto G Antonini L Tassinari CA Occipital lobe seizures related to clinically asymptomatic celiac disease in adulthood Epilepsia 1992 May-Jun 33 3 476 481 10.1111/j.1528-1157.1992.tb01695.x 1592023 Gobbi G Ambrosetto P Zaniboni MG Lambertini A Ambrosioni G Tassinari CA Celiac disease, posterior cerebral calcifications and epilepsy Brain Dev 1992 Jan 14 1 23 29 10.1016/S0387-7604(12)80275-0 1590524