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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-6-59</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-6-8-4</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Headache Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Childhood Cluster Headaches</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>08</month>
<year>1992</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>07</month>
<year>2016</year>
</pub-date>
<volume>6</volume>
<issue>8</issue>
<fpage>59</fpage>
<lpage>60</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1992 The Author(s)</copyright-statement>
<copyright-year>1992</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1111/j.1526-4610.1992.hed3206275.x" vol="32" page="275">
<article-title>Childhood onset cluster headaches</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>Cluster headaches similar to the typical adult form occurred in 35 patients at or before 18 years of age in a study from the Montefiore Medical Center and Schneider Children&#x2019;s Hospital, New York.</p>
</abstract>
<kwd-group>
<kwd>Cluster Headaches</kwd>
<kwd>Lacrimation</kwd>
<kwd>Migraine</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Cluster headaches similar to the typical adult form occurred in 35 patients at or before 18 years of age in a study from the Montefiore Medical Center and Schneider Children&#x2019;s Hospital, New York. The mean age at onset was 14 years (range 5-18). The delay from onset to diagnosis ranged from 0 to 34 years (mean 8 years). Pain was ocular in 88% and lacrimation occurred in 85%. Ptosis was present in 48% and nasal congestion in 60%. A family history of migraine occurred in 9 patients and a family history of cluster headaches in 3. The frequency and duration of cluster periods increased with age in 14. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<disp-quote>
<p><bold>COMMENT.</bold> Familial cluster headache occurring in 3 generations is reported from the Brigham and Women&#x2019;s Hospital, Boston [<xref ref-type="bibr" rid="CIT0002">2</xref>]. The child, an 8-year-old boy, had suffered from headaches since age 4; the father age 42, and the paternal grandfather age 73, had cluster headache also. Three pairs of identical twins with cluster headache have been reported, suggesting a genetic factor in predisposition. [<xref ref-type="bibr" rid="CIT0003">3</xref>, <xref ref-type="bibr" rid="CIT0004">4</xref>]</p>
</disp-quote>
</body>
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