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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-6-48-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-6-6-12</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Congenital Developmental Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Tuberous Sclerosis: Diagnostic Criteria</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>06</month>
<year>1992</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>07</month>
<year>2016</year>
</pub-date>
<volume>6</volume>
<issue>6</issue>
<fpage>48</fpage>
<lpage>48</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1992 The Author(s)</copyright-statement>
<copyright-year>1992</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1177/088307389200700218" vol="7" page="221">
<article-title>Report of the Diagnostic Criteria Committee of the National Tuberous Sclerosis Association</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>The Diagnostic Criteria Committee of the National Tuberous Sclerosis Association reports primary, secondary, and tertiary features of the disease complex and considers the specificity and reliability of the various lesions.</p>
</abstract>
<kwd-group>
<kwd>Diagnostic Criteria</kwd>
<kwd>Tuberous Sclerosis</kwd>
<kwd>Lesions</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>The Diagnostic Criteria Committee of the National Tuberous Sclerosis Association reports primary, secondary, and tertiary features of the disease complex and considers the specificity and reliability of the various lesions. The histological pattern of a lesion when available is generally more reliable than visual or radiographic appearances. Definite, probable and suspect diagnoses are categorized. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<disp-quote>
<p><bold>COMMENT.</bold> In an editorial, Dr. Robert M. Shuman notes that assumptions about the specificity of lesions will need to be tested. The Committee intends these criteria to be adaptable and modified as data are collected.</p>
</disp-quote>
</body>
<back>
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</article>