1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-4-63 10.15844/pedneurbriefs-4-8-9 Neonatal Neurology Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant White Matter Necrosis in Neonates http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 08 1990 01 08 2016 4 8 63 63 Copyright: © 1990 The Author(s) 1990 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. White matter necrosis in very low birth weight infants: neuropathologic and ultrasonographic findings in infants surviving six days or longer

The neuropathologic and ultrasonographic findings in 22 very low birth weight infants surviving at least 6 days are described from Michigan State University, East Lansing, MI., St. Luke's Roosevelt Medical Center and New York Hospital Cornell Medical Center, NY.

 White Matter Necrosis Periventricular Leukomalacia Parenchymal Echogenicity

The neuropathologic and ultrasonographic findings in 22 very low birth weight infants surviving at least 6 days are described from Michigan State University, East Lansing, MI., St. Luke's Roosevelt Medical Center and New York Hospital Cornell Medical Center, NY. White matter necrosis was found in 15 of the 22 subjects and affected hemispheric white matter in ten. The classic features of periventricular leukomalacia were absent from 7 of the 15 infants with necrosis. Intraventricular hemorrhage had occurred in 17. Increased parenchymal echogenicity and ventricular enlargement were present in 67% of infants with white matter necrosis. [1]

COMMENT White matter necrosis need not be restricted to the periventricular regions and ultrasonographic scanning should include more peripheral areas of the brain.

 Paneth N Rudelli R Monte W Rodriguez E Pinto J Kairam R White matter necrosis in very low birth weight infants: neuropathologic and ultrasonographic findings in infants surviving six days or longer J Pediatr 1990 Jun 116 6 975 84 10.1016/S0022-3476(05)80664-X 2189978