1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-3-67-b 10.15844/pedneurbriefs-3-9-5 Toxic Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Dystonia and Cocaine Withdrawal http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 09 1989 01 08 2016 3 9 67 67 Copyright: © 1989 The Author(s) 1989 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Dystonia related to cocaine withdrawal: a case report and pathogenic hypothesis

An acute dystonic episode in a 15-year-old girl during cocaine withdrawal is reported from the Departments of Neurology and Psychiatry, Albert Einstein College of Medicine, Bronx, N.Y. After 16 hours of observation in the hospital without receiving any drugs, she developed generalized dystonia, torticollis, extensor posturing, and high-pitched vocalizations.

 Acute Dystonic Generalized Dystonia Adjustment Disorder

An acute dystonic episode in a 15-year-old girl during cocaine withdrawal is reported from the Departments of Neurology and Psychiatry, Albert Einstein College of Medicine, Bronx, N.Y. After 16 hours of observation in the hospital without receiving any drugs, she developed generalized dystonia, torticollis, extensor posturing, and high-pitched vocalizations. The episode subsided after administration of 50 mg IV diphenhydramine. She was discharged nine days later with diagnosis of adjustment disorder with depressed mood, and cocaine abuse. [1]

COMMENT. There is a high frequency of neuroleptic-induced dystonia reported in cocaine users. Cocaine may lower the threshold to these reactions. This report indicates that dystonic reactions to cocaine withdrawal can occur in the absence of other drugs.

 Choy-Kwong M Lipton RB Dystonia related to cocaine withdrawal: a case report and pathogenic hypothesis Neurology 1989 Jul 39 7 996 997 10.1212/WNL.39.7.996-a 2739932