1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-3-76 10.15844/pedneurbriefs-3-10-5 Intracranial Tumors Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant West Syndrome and Cerebral Tumors http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 10 1989 01 08 2016 3 10 76 77 Copyright: © 1989 The Author(s) 1989 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Intracranial tumors and West syndrome

Two infants, six and seven months of age, with West syndrome associated with cerebral tumors are reported from the Department of Neurology, Pediatric Hospital, Buenos Aires, Argentina.

 Anaplastic Ependymoma Ependymoma Neurologic Examinations

Two infants, six and seven months of age, with West syndrome associated with cerebral tumors are reported from the Department of Neurology, Pediatric Hospital, Buenos Aires, Argentina. Initial neurologic examinations were normal and the diagnosis of the tumors was by ultrasound and CT. One infant had a Grade III glioma in the right thalamus and the other had an anaplastic ependymoma and cyst in the right hemisphere. EEGs revealed generalized hypsarrhythmia in both cases. Infantile spasms responded to ACTH 5 IU/kg/day. One patient died at 18 months of age and the other was seizure free after complete surgical resection of the ependymoma. [1]

COMMENT. Other brain tumors associated with West syndrome have included choroid plexus papilloma, ganglioglioma, and optic nerve glioma. Infantile spasms and choroid plexus papilloma have also been described in Aicardi syndrome (see Ped Neurol Briefs October 1989; 3:74).

 Ruggieri V Caraballo R Fejerman N Intracranial tumors and West syndrome Pediatr Neurol 1989 Sep-Oct 5 5 327 9 2553029 10.1016/0887-8994(89)90029-5