<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="article-commentary" dtd-version="1.0" xml:lang="en">
<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-3-74-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-3-10-3</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Congenital Malformations</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Arnold-Chiari Malformation</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>10</month>
<year>1989</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>08</month>
<year>2016</year>
</pub-date>
<volume>3</volume>
<issue>10</issue>
<fpage>74</fpage>
<lpage>75</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1989 The Author(s)</copyright-statement>
<copyright-year>1989</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1002/ana.410260317" vol="26" page="401">
<article-title>Intermittent obstructive hydrocephalus in the Arnold-Chiari malformation</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>Intermittent symptoms of obstructive hydrocephalus in a young woman with Chiari-I malformation are reported from the Neuro-Ophthalmology Service, Wills Eye Hospital, Philadelphia, PA.</p>
</abstract>
<kwd-group>
<kwd>Intermittent Symptoms</kwd>
<kwd>Blurred Vision</kwd>
<kwd>Green Patch</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Intermittent symptoms of obstructive hydrocephalus in a young woman with Chiari-I malformation are reported from the Neuro-Ophthalmology Service, Wills Eye Hospital, Philadelphia, PA. A previously healthy 26 year old woman experienced episodes of intermittent pressure headaches, dizziness, tingling in the right arm, and right anterior chest pressure for two months. These episodes lasted 5-15 minutes and occurred up to 15 times a day. They were followed by blurred vision with the appearance a &#x201C;green patch&#x201D; inferiorly before the left eye. Bilateral optic disc elevation was identified with indirect ophthalmoscopy. Lumbar puncture showed an opening pressure of 190 mm H<sub>2</sub>O. Intravenous fluorescein angiography demonstrated venous stasis, diffuse retinal hemorrhages, and disc edema interpreted as consistent with papillophlebitis. An MRI using multiple thin sagittal sections directed at the posterior fossa revealed the Chiari I malformation, and an intraventricular catheter confirmed that the malformation was causing an intermittent obstruction and increased intracranial pressure. In one attack in which the patient experienced several typical episodes of right hand and right chest paresthesias, headache, and blurred vision the simultaneous intracranial pressure readings were elevated to a maximum of 580 mm H<sub>2</sub>O. The pressure was sustained for approximately 2 minutes; as it decreased the patient&#x2019;s symptoms abated. Following posterior fossa decompression and a C1 to C3 laminectomy the pressure was relieved and the patient was asymptomatic. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<disp-quote>
<p><underline>COMMENT</underline>. Although this patient is outside the pediatric age group, Chiari I malformation becomes symptomatic in children and the transient nature of the signs and symptoms may prove misleading in diagnosis. Conventional CT and MRI may fail to reveal the malformation and posterior fossa directed MRI using multiple thin sagittal sections including the midline view may be necessary for diagnosis.</p>
</disp-quote>
</body>
<back>
<ref-list>
<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Vrabec</surname>
<given-names>TR</given-names>
</name>
<name>
<surname>Sergott</surname>
<given-names>RC</given-names>
</name>
<name>
<surname>Savino</surname>
<given-names>PJ</given-names>
</name>
<name>
<surname>Bosley</surname>
<given-names>TM</given-names>
</name>
</person-group>
<article-title>Intermittent obstructive hydrocephalus in the Arnold-Chiari malformation</article-title>
<source>Ann Neurol</source>
<year>1989</year>
<month>Sep</month>
<volume>26</volume>
<issue>3</issue>
<fpage>401</fpage>
<lpage>4</lpage>
<pub-id pub-id-type="pmid">2802539</pub-id>
<pub-id pub-id-type="doi">10.1002/ana.410260317</pub-id>
</element-citation>
</ref>
</ref-list>
</back>
</article>
