1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-23-92-a 10.15844/pedneurbriefs-23-12-4 Language Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Effect of Temporal Lobectomy for Epilepsy on Language Development http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 12 2009 01 12 2015 23 12 92 92 Copyright: © 2009 The Author(s) 2009 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Language development before and after temporal surgery in children with intractable epilepsy

Language development was examined in 24 children (mean age 11 years; range 5.8-15.7 years) with AED intractable epilepsy before and 6, 12, and 24 months after anterior temporal lobectomy, in a study by the Dutch Collaborative Epilepsy Surgery Programme (DuCESP) at University Medical Center Utrecht, The Netherlands.

 Language Development Dutch Collaborative Epilepsy Surgery Programme Lobe Epilepsy

Language development was examined in 24 children (mean age 11 years; range 5.8-15.7 years) with AED intractable epilepsy before and 6, 12, and 24 months after anterior temporal lobectomy, in a study by the Dutch Collaborative Epilepsy Surgery Programme (DuCESP) at University Medical Center Utrecht, The Netherlands. Before surgery, the mean language delay varied from 1.7 years to 3.5 years and after surgery, language development was slower than normal, except for receptive syntax (execution of oral commands). Productive lexicon (oral response to visually presented objects) was slowed when surgery and language mediation were both in the left hemisphere. [1]

COMMENT. Intractable temporal lobe epilepsy is a risk factor for delay in language development, and surgery does not result in improved language. Some language components are slowed when surgery and language mediation both involve the left hemisphere. Temporal lobectomy of the non-dominant hemisphere is not expected to affect language development.

de Koning T Versnel H Jennekens-Schinkel A van Schooneveld MM Dejonckere PH van Rijen PC Language development before and after temporal surgery in children with intractable epilepsy Epilepsia 2009 Nov 50 11 2408 2419 10.1111/j.1528-1167.2009.02264.x 19674043