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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-23-05-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-23-1-6</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Movement Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Behavioral Disorders in Children with Tourette Syndrome</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Ann &#x0026; Robert H. Lurie Children&#x0027;s Hospital of Chicago, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>01</month>
<year>2009</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>12</month>
<year>2015</year>
</pub-date>
<volume>23</volume>
<issue>1</issue>
<fpage>5</fpage>
<lpage>5</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2009 The Author(s)</copyright-statement>
<copyright-year>2009</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1016/j.braindev.2008.03.010" vol="31" page="15">
<article-title>Psychiatric disorders and behavioral problems in children and adolescents with Tourette syndrome</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>The prevalence of comorbid neurobehavioral problems in 35 children and adolescents (31 [88%] boys; mean age 11.8 years) with Tourette syndrome (TS) was determined at a psychiatric clinic at Shiraz University of Medical Sciences, Hafez Hospital, Iran.</p>
</abstract>
<kwd-group>
<kwd>Coprolalia</kwd>
<kwd>Tourette Syndrome</kwd>
<kwd>Comorbid Disruptive</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>The prevalence of comorbid neurobehavioral problems in 35 children and adolescents (31 [88%] boys; mean age 11.8 years) with Tourette syndrome (TS) was determined at a psychiatric clinic at Shiraz University of Medical Sciences, Hafez Hospital, Iran. Motor tics were blinking (54%), mouth (31%) and shoulder (31%) movements. Vocal tics were throat clearing and grunting. Coprolalia occurred in 9%. Comorbid disruptive behavior disorders were ADHD in 24 (68%); ODD (28%); and CD in 5.7%. TS+disruptive behaviors occurred in 71%, TS+anxiety disorders in 43% (OCD 26%), TS+mood disorders in 14%. TS patients without comorbidity were uncommon (2.9%), and less than previously reported. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<p>COMMENT. Almost all patients with TS have some behavioral comorbid disorder. ADHD is the most common comorbid disorder, followed by ODD and OCD. Mood disorders are uncommon.</p>
</body>
<back>
<ref-list>
<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Ghanizadeh</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Mosallaei</surname>
<given-names>S</given-names>
</name>
</person-group>
<article-title>Psychiatric disorders and behavioral problems in children and adolescents with Tourette syndrome</article-title>
<source>Brain Dev</source>
<year>2009</year>
<month>Jan</month>
<volume>31</volume>
<issue>1</issue>
<fpage>15</fpage>
<lpage>9</lpage>
<pub-id pub-id-type="doi">10.1016/j.braindev.2008.03.010</pub-id>
<pub-id pub-id-type="pmid">18558469</pub-id>
</element-citation>
</ref>
</ref-list>
</back>
</article>
