1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-22-94-b 10.15844/pedneurbriefs-22-12-9 Neonatal Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Hippocampal Volumes in Preterm Infants http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 12 2008 01 02 2016 22 12 94 95 Copyright: © 2008 The Author(s) 2008 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Preterm infant hippocampal volumes correlate with later working memory deficits

The relation between neonatal regional brain volumes and working memory deficits at age 2 years was investigated in 156 very preterm children born at the Royal Women’s Hospital, Melbourne, Auatralia, prior to 30 weeks gestation or weighing <1250g.

 Hippocampal Volumes Preterm Children Memory Deficit

The relation between neonatal regional brain volumes and working memory deficits at age 2 years was investigated in 156 very preterm children born at the Royal Women’s Hospital, Melbourne, Auatralia, prior to 30 weeks gestation or weighing <1250g. Very preterm children who perseverated on the working memory task had significantly smaller hippocampal volumes than controls with intact working memory. [1]

COMMENT. Children born preterm have smaller hippocampal volumes that correlate with working memory deficits measured at 2 years of age. Further research will determine the longterm effect of altered hippocampal volumes on cognitive function of premature infants.

Beauchamp MH Thompson DK Howard K Doyle LW Egan GF Inder TE Preterm infant hippocampal volumes correlate with later working memory deficits Brain 2008 Nov 131 Pt 11 2986 94 10.1093/brain/awn227 18799516