1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-2-67-b 10.15844/pedneurbriefs-2-9-5 Neonatal Cerebro-Vascular Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Neonatal Stroke Outcome http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 09 1988 01 08 2016 2 9 67 68 Copyright: © 1988 The Author(s) 1988 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Outcome of neonatal strokes

The clinical outcome of 17 children, 1 to 11 years of age, who experienced cerebral artery infarctions as neonates has been studied in the Depts of Pediatrics and Neurology, Univ of Kentucky Med Center, Lexington, Kentucky.

 Cerebral Artery Infarctions Middle Cerebral Artery Normal Neurologic Development

The clinical outcome of 17 children, 1 to 11 years of age, who experienced cerebral artery infarctions as neonates has been studied in the Depts of Pediatrics and Neurology, Univ of Kentucky Med Center, Lexington, Kentucky. The left middle cerebral artery (MCA) was involved in 9 (53%) and the right MCA in 5 (30%). Fourteen (82%) who developed neonatal seizures became seizure free and neurologically normal within the first year and anticonvulsants were discontinued. Three patients had recurrence of seizures after 1 to 8 years and anticonvulsants were renewed. Eleven patients (65%) have normal neurologic development but one of 2 attending school has cognitive deficits. [1]

COMMENT. The authors conclude that infants with a unilateral arterial stroke generally have a favorable prognosis initially but require long-term follow up for possible recurrence of seizures and development of learning disabilities. Comparing these results with a previous report of neonatal stroke (See Ped Neur Briefs Aug 1988;2: 63-64 ), the increased prevalence of left middle cerebral artery infarction and the frequent complication of neonatal seizures are in agreement, but the recovery of neurologic function within 1 year is in contrast to a persistent hemiparesis in 66% of patients examined at 1-4 years of age.

 Sran SK Baumann RJ Outcome of neonatal strokes Am J Dis Child 1988 Oct 142 10 1086 8 10.1001/archpedi.1988.02150100080031 3177305