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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-2-59-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-2-8-5</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Toxic Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Fetal Alcohol Syndrome</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>08</month>
<year>1988</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>08</month>
<year>2016</year>
</pub-date>
<volume>2</volume>
<issue>8</issue>
<fpage>59</fpage>
<lpage>60</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1988 The Author(s)</copyright-statement>
<copyright-year>1988</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="pmid" xlink:href="3399287" vol="82" page="147">
<article-title>Hearing disorders in children with fetal alcohol syndrome: findings from case reports</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>Hearing and speech and language development in 14 children with fetal alcohol syndrome were evaluated at the Fetal Alcohol Research Center, Wayne State University School of Medicine, Detroit, Michigan, and the Audiology Division, School of Medicine, University of Colorado Health Sciences Center, Denver, Colorado.</p>
</abstract>
<kwd-group>
<kwd>Fetal Alcohol Syndrome</kwd>
<kwd>Hearing Disorders</kwd>
<kwd>Learning Disabilities</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Hearing and speech and language development in 14 children with fetal alcohol syndrome were evaluated at the Fetal Alcohol Research Center, Wayne State University School of Medicine, Detroit, Michigan, and the Audiology Division, School of Medicine, University of Colorado Health Sciences Center, Denver, Colorado. Recurrent serous otitis media with hearing loss and speech and language problems occurred in 13, and 4 also had sensorineural hearing loss. The IQ was 70-85 in 7 children and below 69 in 7. The authors conclude that hearing disorders are a significant complication of fetal alcohol exposure, probably contributing to the speech and language and learning disabilities commonly associated with the syndrome. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<disp-quote>
<p><bold><underline>COMMENT</underline>.</bold> As a cause of mental retardation, fetal alcohol syndrome is as prevalent as Down&#x0027;s syndrome and occurs in at least one in 1000 births. Postmortem examination of the brain reveals extensive developmental defects, mostly the consequence of migration anomalies. Heterotopias, lissencephaly, and agenesis of the corpus callosum have been described. Migration anomalies may involve the brain stem as well as the cerebrum, thus accounting for the sensorineural deafness noted in the above study.</p>
</disp-quote>
</body>
<back>
<ref-list>
<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Church</surname>
<given-names>MW</given-names>
</name>
<name>
<surname>Gerkin</surname>
<given-names>KP</given-names>
</name>
</person-group>
<article-title>Hearing disorders in children with fetal alcohol syndrome: findings from case reports</article-title>
<source>Pediatrics</source>
<year>1988</year>
<month>Aug</month>
<volume>82</volume>
<issue>2</issue>
<fpage>147</fpage>
<lpage>154</lpage>
<pub-id pub-id-type="pmid">3399287</pub-id>
</element-citation>
</ref>
</ref-list>
</back>
</article>