1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-2-21-a 10.15844/pedneurbriefs-2-3-8 Infantile Seizures Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Infantile Spasms http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 03 1988 01 08 2016 2 3 21 21 Copyright: © 1988 The Author(s) 1988 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Partial seizures evolving to infantile spasms

Four infants with partial seizures evolving to infantile spasms were investigated using simultaneous EEG-video-telemetry recording in the Dept of Pediatrics, Nagoya University, Nagoya, and Division of Pediatric Neurology, Central Hospital, Aichi Prefectural Colony, Kasugai, Japan.

 EEG-Video-Telemetry Infantile Spasms EEG Abnormalities

Four infants with partial seizures evolving to infantile spasms were investigated using simultaneous EEG-video-telemetry recording in the Dept of Pediatrics, Nagoya University, Nagoya, and Division of Pediatric Neurology, Central Hospital, Aichi Prefectural Colony, Kasugai, Japan. Partial seizures were characterized by cessation of activity, staring, flushing, automatisms, increased tone and laughter. [1]

COMMENT. A cry or scream is the most common ictal element in infantile spasms, and laughter and a frightened or confused expression, manifestations of partial seizures, are frequently described [2]. The above report appears to be the first in which infantile spasms were preceded by partial seizures confirmed by EEG-VT. However, one of the above authors, in a previous study of the evolution of EEG abnormalities accompanying infantile spasms, reported hypsarrhythmia preceded by focal sharp wave patterns, compatible with partial seizures. [3]

 Yamamoto N Watanabe K Negoro T Furune S Takahashi I Nomura K Partial seizures evolving to infantile spasms Epilepsia 1988 Jan-Feb 29 1 34 40 10.1111/j.1528-1157.1988.tb05095.x 3123212 Jeavons PM Bower BD Clinics in Developmental Medicine No 15 1964 London Spastics Society and Heinemann Watanabe K Iwase K Hara K The evolution of EEG features in infantile spasms: a prospective study Dev Med Child Neurol 1973 Oct 15 5 584 96 10.1111/j.1469-8749.1973.tb05169.x 4358106