1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-2-24 10.15844/pedneurbriefs-2-3-13 Movement Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Tourette's Syndrome http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 03 1988 01 08 2016 2 3 24 24 Copyright: © 1988 The Author(s) 1988 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Tourette's syndrome in Monroe County school children

The prevalence of Gilles de la Tourette's syndrome (TS) in school children from Monroe County, New York, was examined in the Depts of Psychiatry, Neurology and Pediatrics, University of Rochester Medical Center, Rochester, NY.

 Tourette's Syndrome Attention Deficit Disorder with Hyperactivity Functional Psychiatric Causes

The prevalence of Gilles de la Tourette's syndrome (TS) in school children from Monroe County, New York, was examined in the Depts of Psychiatry, Neurology and Pediatrics, University of Rochester Medical Center, Rochester, NY. Forty-one TS patients were detected with an estimated prevalence of 28.7 per 100,000. Twenty (50%) of the 41 children had obsessive ideas or ritualistic motor behaviors associated with obsessive ideas. These included rituals to make sure the body was symmetrical or balanced, mental arithmetic games, touching of objects to ward off bad luck, or repetitively placing objects. Only 3 had a diagnosable obsessive-compulsive disorder. Eleven children had attention deficit disorder with hyperactivity (ADDH); of 10 who had received methylphenidate, one developed tics after 18 months of therapy and movements almost completely ceased when drug was discontinued. Eleven had insomnia and seven had self-harming behaviors, including lip biting, sticking pins in the skin, and burning fingers on hot objects. Twenty patients had complex vocalizations including copOrolalia, echolalia and stuttering. On neurologic examination, 12 showed subtle abnormalities or soft signs including synkinesis, impaired rapid alternating movements, and inability to hop, and one had significant postural and motor defects associated with microcephaly and growth retardation. Thirty-seven were male and four were female. Fifty-six percent had a positive family history of TS or tics. TS was a mild disorder requiring no drug reatment in 23 (56%) patients. Thirteen of those who received haloperidol (0.5-2.5mg daily) were benefited and 5 patients were uncontrolled. [1]

COMMENT. Tourette's syndrome is manifested by the onset of recurrent multiple motor tics and involuntary vocal tics in childhood. The incidence of reported cases was low until the 1960s and the condition was generally omitted from the index of textbooks of neurology. Increased public awareness of the disorder and recognition of organic in addition to functional psychiatric causes have led to an increase in apparent prevalence. Formerly, the combination of tics, coprolalia and barking were required for diagnosis whereas recently, patients with simple habit spasms are sometimes included in collected series. The exact etiology is unknown although organic factors are suspected. About 10% have a history of previous head injury or neonatal asphyxia [2]. Many have learning problems and behavior disorders for which psychostimulant medication may be indicated. Methylphenidate should be withheld or used with caution at lower dose levels in children with tics or a family history of Tourette's syndrome.

 Caine ED McBride MC Chiverton P Bamford KA Rediess S Shiao J Tourette's syndrome in Monroe County school children Neurology 1988 Mar 38 3 472 5 10.1212/WNL.38.3.472 3162295 Erenberg G Cruse RP Rothner AD Tourette syndrome: an analysis of 200 pediatric and adolescent cases Cleve Clin Q 1986 53 2 127 31 10.3949/ccjm.53.2.127 3461891