1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-2-76-a 10.15844/pedneurbriefs-2-10-5 Involuntary Movement Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Transient Tics and Tourette's Syndrome http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 11 1988 01 08 2016 2 10 76 76 Copyright: © 1988 The Author(s) 1988 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Transient tic disorder and the spectrum of Tourette's syndrome

The relation of transient tic disorder (TTD - motor or vocal tics lasting less than 1 year) to Tourette's syndrome (TS multiple motor and vocal tics lasting longer than 1 year) has been evaluated in two Canadian Mennonite families at the Dept of Neurology, Univ of Rochester Sch of Med, NY.

 Transient Tic Disorder Tourette's Syndrome Chronic Tic Disorder

The relation of transient tic disorder (TTD - motor or vocal tics lasting less than 1 year) to Tourette's syndrome (TS multiple motor and vocal tics lasting longer than 1 year) has been evaluated in two Canadian Mennonite families at the Dept of Neurology, Univ of Rochester Sch of Med, NY. One girl aged 9 yrs experienced frequent repetitive throat clearing and eye blinking episodes that resolved after several months (TTD). Her father and brother had TS and 2 siblings had chronic tic disorder (CTC-motor or vocal tics, but not both, with duration more than 1 year). A boy aged 12 yrs had frequent head jerks resolving over several months (TTD). His father had TS and sibling had CTD. In adulthood, the patient had 3 chldren, one with TS, [1].

COMMENT. Transient tic disorder may be an expression of the TS gene that may be transmitted to offspring as an autosomal dominant. The frequency of transient tics in childhood is quoted at 4-16%. The observations in this study suggest that TS and related tic disorders are more prevalent than generally appreciated.

 Kurlan R Behr J Medved L Como P Transient tic disorder and the spectrum of Tourette's syndrome Arch Neurol 1988 Nov 45 11 1200 1 10.1001/archneur.1988.00520350038012 3190500