<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="article-commentary" dtd-version="1.0" xml:lang="en">
<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-19-94-a</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-19-12-7</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Headache Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Multidisciplinary Treatment of Pediatric Migraine</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>12</month>
<year>2005</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>03</month>
<year>2016</year>
</pub-date>
<volume>19</volume>
<issue>12</issue>
<fpage>94</fpage>
<lpage>94</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2005 The Author(s)</copyright-statement>
<copyright-year>2005</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1111/j.1526-4610.2005.00261.x" vol="45" page="1298">
<article-title>Outcome of a multidisciplinary approach to pediatric migraine at 1, 2, and 5 years</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>The long-term effectiveness and outcome of multidisciplinary treatment of childhood headaches were evaluated at 1, 2, and 5 years at the Cincinnati Children&#x2019;s Hospital Medical Center, OH.</p>
</abstract>
<kwd-group>
<kwd>Multidisciplinary Treatment of Childhood Headaches</kwd>
<kwd>Prophylactic</kwd>
<kwd>Topiramate</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>The long-term effectiveness and outcome of multidisciplinary treatment of childhood headaches were evaluated at 1, 2, and 5 years at the Cincinnati Children&#x2019;s Hospital Medical Center, OH. Diagnosis was based on clinical impression and ICHD criteria. Data on severity, frequency, duration, participation in activities during headaches, effect of treatment, and school days missed were collected from clinic follow-up questionnaire or via telephone. The team-based treatment plan included acute, prophylactic, behavioral therapy, and teaching. Bio-behavioral therapy included changes in diet, hydration, sleep pattern, and activity. Days of school missed were used as a disability measure; a marked decrease occurred from 4.5+/-9.5 at initial visit to 1.55+/-2.8 at 5 years (p&#x003C;0.001). Headache frequency was 13.4/month initially, 4.9 at 1 year, 4.7 at 2 years, and 4.5 at 5 years (p&#x003C;0.001). Headache severity was also significantly decreased. Patients with less frequent and shorter duration headaches at initial visit were less likely to return for follow-up, but continued to do well at 5-year assessment. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<p>COMMENT. Children with more severe migraine headaches at initial presentation should benefit from a regular multidisciplinary treatment plan.</p>
<p>Topiramate was effective in reducing the frequency and severity of chronic daily headache in 62% of 21 patients, ages 6-18 years, using a low dose (average 30/mg/day). [<xref ref-type="bibr" rid="CIT0002">2</xref>]</p>
</body>
<back>
<ref-list>
<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Kabbouche</surname>
<given-names>MA</given-names>
</name>
<name>
<surname>Powers</surname>
<given-names>SW</given-names>
</name>
<name>
<surname>Vockell</surname>
<given-names>AL</given-names>
</name>
<name>
<surname>LeCates</surname>
<given-names>SL</given-names>
</name>
<name>
<surname>Ellinor</surname>
<given-names>PL</given-names>
</name>
<name>
<surname>Segers</surname>
<given-names>A</given-names>
</name>
<etal/>
</person-group>
<article-title>Outcome of a multidisciplinary approach to pediatric migraine at 1, 2, and 5 years</article-title>
<source>Headache</source>
<year>2005</year>
<month>Nov-Dec</month>
<volume>45</volume>
<issue>10</issue>
<fpage>1298</fpage>
<lpage>1303</lpage>
<pub-id pub-id-type="doi">10.1111/j.1526-4610.2005.00261.x</pub-id>
<pub-id pub-id-type="pmid">16324161</pub-id>
</element-citation>
</ref>
<ref id="CIT0002">
<label>2</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Borzy</surname>
<given-names>JC</given-names>
</name>
<name>
<surname>Koch</surname>
<given-names>TK</given-names>
</name>
<name>
<surname>Schimschock</surname>
<given-names>JR</given-names>
</name>
</person-group>
<article-title>Effectiveness of topiramate in the treatment of pediatric chronic daily headache</article-title>
<source>Pediatr Neurol</source>
<year>2005</year>
<month>Nov</month>
<volume>33</volume>
<issue>5</issue>
<fpage>314</fpage>
<lpage>316</lpage>
<pub-id pub-id-type="doi">10.1016/j.pediatrneurol.2005.06.001</pub-id>
<pub-id pub-id-type="pmid">16243217</pub-id>
</element-citation>
</ref>
</ref-list>
</back>
</article>
