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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-18-80-a</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-18-10-9</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Neoplasms and Malformations</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Surgical Treatment of Spinal Tumors</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>10</month>
<year>2004</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>03</month>
<year>2016</year>
</pub-date>
<volume>18</volume>
<issue>10</issue>
<fpage>80</fpage>
<lpage>80</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2004 The Author(s)</copyright-statement>
<copyright-year>2004</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1016/j.pediatrneurol.2004.03.019" vol="31" page="261">
<article-title>The clinical and surgical aspects of spinal tumors in children</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>A series of 20 spinal tumors in children who underwent surgery between 1995 and 2003 is reported from Gulhane Military Medical Academy, Ankara, Turkey.</p>
</abstract>
<kwd-group>
<kwd>Epidural Tumors</kwd>
<kwd>Lumbosacral Region</kwd>
<kwd>Low-Grade Astrocytoma</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>A series of 20 spinal tumors in children who underwent surgery between 1995 and 2003 is reported from Gulhane Military Medical Academy, Ankara, Turkey. Time of diagnosis ranged from 1 to 16 years (mean age, 4.85 years). Initial signs were motor weakness in 60% (mainly upper motor), reflex changes 50% (hyperactive DTRs, loss of superficial reflexes, Babinski responses), sensory changes 45%, subcutaneous mass lesion 15%, and atrophy of lower limb muscles in 10%. Time between onset of signs and diagnosis ranged from 1 month to 3 years (mean, 8.5 months). Epidural tumors occurred in 8 (40%), intradural-extramedullary in 8 (40%), and intradural-intramedullary in 4 (20%) patients. Tumors were located in the lumbar or lumbosacral region in 8 (40%) patients, thoracic in 5, and cervical and cervicothoracic in 3. Complete removal of the tumor was achieved in 16 (80%). These were primitive neuroectodermal, low-grade astrocytoma, ependymoma, teratoma, schwannoma, neuroblastoma, and dermoid tumors. Subtotal surgical excision was possible in the remaining 4 (20%) patients with lipoma and sarcoma. Laminotomy was preferred in 12 (60%) patients under 3 years of age who required extensive surgical exposure, and laminectomy in 8 (40%). Nine (45%) underwent postoperative chemotherapy and radiotherapy; these were teratoma, sarcoma, and neuroectodermal. During 9 to 60 months follow-up (mean, 22 months), 3 with sarcoma and neuroblastoma died, the postsurgical course was complicated by infection and CSF leakage in 2, and 15 patients were free of tumor. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<p>COMMENT. Tumors of the spinal canal comprise 5 to 10% of CNS tumors in children. A male preponderance is usually observed. Thirty-five percent are located epidurally. A delayed deformity of the spine may occur after surgery, most frequently in patients younger than 15 years. No cases of spinal deformity occurred in the above series.</p>
<p><bold>Spinal fibrous hamartoma in a 10 month old infant</bold> is reported from University of Hokkaido, Sapporo, Japan [<xref ref-type="bibr" rid="CIT0002">2</xref>]. The infant presented with paraparesis and MRI showed an intradural mass at T10-L4. At laminectomy, the tumor was partially removed, and symptoms were unchanged. At 8 months follow-up, no further growth of tumor had occurred.</p>
</body>
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