1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-14-54-a 10.15844/pedneurbriefs-14-7-10 Movement Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Volumetric MRI in Tourette Syndrome: A Gender Effect http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 07 2000 01 04 2016 14 7 54 54 Copyright: © 2000 The Author(s) 2000 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Subcortical volumes in girls with tourette syndrome: support for a gender effect

Subcortical volumetric MRIs were compared in 19 girls (aged 7 to 15 years) with Tourette syndrome (TS) and 21 controls.

 Subcortical Volumetric MRI Tourette Syndrome Putamen Asymmetry

Subcortical volumetric MRIs were compared in 19 girls (aged 7 to 15 years) with Tourette syndrome (TS) and 21 controls. Eleven of the patients had TS only and 8 had TS with attention deficit hyperactivity disorder (TS + ADHD). TS-only patients had significantly smaller lateral ventricles compared with TS + ADHD patients and the control subjects. Putamen asymmetry index as a marker for TS, previously demonstrated in boys with TS, was present in girls with TS and also in control girls with no TS. [1]

COMMENT. In contrast to previous studies involving mainly boys, abnormal lenticular asymmetry does not occur in girls with Tourette syndrome. Girls, with or without TS, exhibit the putamen asymmetry seen in boys. TS-only girls differed from TS + ADHD girls and controls in having significantly smaller lateral ventricles. Future investigations of TS should make distinctions of gender and patients with and without ADHD.

Zimmerman AM Abrams MT Giuliano JD Denckla MB Singer HS Subcortical volumes in girls with tourette syndrome: support for a gender effect Neurology 2000 Jun 27 54 12 2224 2229 10.1212/WNL.54.12.2224 10881244