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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-12-69-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-12-9-7</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Neuromuscular Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Prognosis of Benign Congenital Hypotonia</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>09</month>
<year>1998</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>04</month>
<year>2016</year>
</pub-date>
<volume>12</volume>
<issue>9</issue>
<fpage>69</fpage>
<lpage>70</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1998 The Author(s)</copyright-statement>
<copyright-year>1998</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1111/j.1469-8749.1998.tb15394.x" vol="40" page="448">
<article-title>Developmental correlates of school-age children with a history of benign congenital hypotonia</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>Twenty five children diagnosed with benign congenital hypotonia (BCH) between infancy and 2 years of age were examined at 6 to 8 years of age and compared to 26 controls, matched for sex, age, and weight, in a study at the School of Occupational Therapy, Hebrew University-Hadassah Medical School, and Child Development Institute, Jerusalem.</p>
</abstract>
<kwd-group>
<kwd>Benign Congenital Hypotonia</kwd>
<kwd>Visual-Perception</kwd>
<kwd>Normal Muscle Tone</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Twenty five children diagnosed with benign congenital hypotonia (BCH) between infancy and 2 years of age were examined at 6 to 8 years of age and compared to 26 controls, matched for sex, age, and weight, in a study at the School of Occupational Therapy, Hebrew University-Hadassah Medical School, and Child Development Institute, Jerusalem. Sensory, visual-perception, visual-motor integration, and behavioral measures were similar in the 2 groups, but the BCH group showed impairments in gross motor performance, bilateral coordination and strength on the Oseretsky Test of Motor Proficiency, despite recovery of near normal muscle tone. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<p>COMMENT. Children diagnosed with benign congenital hypotonia in infancy should be reexamined at intervals through early childhood and should receive extended occupational and other therapy to build muscle strength, balance, and coordination. Hypotonic infants may appear to recover near normal tone by 6 years of age but demonstrate clumsiness and generalized muscle weakness on tests of motor proficiency. My own clinical experience would substantiate these findings. Whereas the office neurological examination appears normal, the mother complains that the child lacks normal stamina, tires easily on extended walks, and often wants to be carried. The symptoms described are sometimes suggestive of a possible myasthenia.</p>
</body>
<back>
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<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
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<volume>40</volume>
<issue>7</issue>
<fpage>448</fpage>
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<pub-id pub-id-type="doi">10.1111/j.1469-8749.1998.tb15394.x</pub-id>
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</article>