1043-3155 Pediatr Neurol Briefs pedneurbriefs Pediatr Neurol Briefs Pediatric Neurology Briefs Pediatr Neurol Briefs 2166-6482 1043-3155 2166-3155 Pediatric Neurology Briefs Publishers Chicago, IL, USA PNB-12-62-b 10.15844/pedneurbriefs-12-8-10 Vascular Disorders Neurology Pediatrics Nervous System Diseases Child Development Brain Diseases Neurosurgery Child Infant Cerebral Vasculitis in Juvenile Rheumatoid Arthritis http://orcid.org/0000-0002-0173-7931 Millichap J. Gordon MD 1 2 * Division of Neurology, Children's Memorial Hospital, Chicago, IL Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL Correspondence: Dr. J. Gordon Millichap, E-mail: jgmillichap@northwestern.edu 08 1998 01 05 2016 12 8 62 63 Copyright: © 1998 The Author(s) 1998 This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cerebral vasculitis in an adolescent with juvenile rheumatoid arthritis

A 16-year-old girl who developed a stroke after a 5-year history of polyarticular juvenile rheumatoid arthritis is reported from Tripler Army Medical Center, Honolulu, Hawaii.

 Juvenile Rheumatoid Arthritis Cerebral Vein Thrombosis Systemic Lupus Erythematosus

A 16-year-old girl who developed a stroke after a 5-year history of polyarticular juvenile rheumatoid arthritis is reported from Tripler Army Medical Center, Honolulu, Hawaii. She was referred from Chuuk State, Micronesia, because of right hemiparesis, facial weakness, joint pains, and cataract. MR angiography revealed vasculitis of the anterior and middle cerebral arteries. Both clinical and MR findings improved following treatment with methylprenisolone. Outpatient treatment with oral methotrexate, predisone, and aspirin resulted in complete remission. [1]

COMMENT. Juvenile rheumatoid arthritis is an unusual cause of cerebral vasculitis and stroke in children. Cerebral vein thrombosis (CVT) and infarct associated with systemic lupus erythematosus (SLE) is reviewed in Progress in Pediatric Neurology III, PNB Publ, 1997;pl73. Three girls with SLE and CVT, ages 11, 14, and 17, presented with a severe, persistent throbbing headache, unresponsive to analgesics.

Pedersen RC Person DA Cerebral vasculitis in an adolescent with juvenile rheumatoid arthritis Pediatr Neurol 1998 Jul 19 1 69 73 10.1016/S0887-8994(98)00022-8 9682891