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<front>
<journal-meta>
<journal-id journal-id-type="issn">1043-3155</journal-id>
<journal-id journal-id-type="nlm-ta">Pediatr Neurol Briefs</journal-id>
<journal-id journal-id-type="pmc">pedneurbriefs</journal-id>
<journal-id journal-id-type="iso-abbrev">Pediatr Neurol Briefs</journal-id>
<journal-title-group>
<journal-title>Pediatric Neurology Briefs</journal-title>
<abbrev-journal-title>Pediatr Neurol Briefs</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2166-6482</issn>
<issn pub-type="ppub">1043-3155</issn>
<issn-l>2166-3155</issn-l>
<publisher>
<publisher-name>Pediatric Neurology Briefs Publishers</publisher-name>
<publisher-loc>Chicago, IL, USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">PNB-11-96-b</article-id>
<article-id pub-id-type="doi">10.15844/pedneurbriefs-11-12-13</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Seizure Disorders</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v2">
<subject>Neurology</subject>
<subject>Pediatrics</subject>
<subject>Nervous System Diseases</subject>
<subject>Child Development</subject>
<subject>Brain Diseases</subject>
<subject>Neurosurgery</subject>
<subject>Child</subject>
<subject>Infant</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Electroconvulsive Therapy for Intractable Seizures</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-0173-7931</contrib-id>
<name>
<surname>Millichap</surname>
<given-names>J. Gordon</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="AF0001">1</xref>
<xref ref-type="aff" rid="AF0002">2</xref>
<xref ref-type="corresp" rid="cor1">&#x002A;</xref>
</contrib>
</contrib-group>
<aff id="AF0001">
<label>1</label>Division of Neurology, Children&#x0027;s Memorial Hospital, Chicago, IL</aff>
<aff id="AF0002">
<label>2</label>Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</aff>
<author-notes>
<corresp id="cor1"><label>&#x002A;</label>Correspondence: Dr. J. Gordon Millichap, E-mail: <email xlink:href="jgmillichap@northwestern.edu">jgmillichap@northwestern.edu</email>
</corresp>
</author-notes>
<pub-date date-type="pub" publication-format="print">
<month>12</month>
<year>1997</year>
</pub-date>
<pub-date date-type="pub" publication-format="electronic">
<day>01</day>
<month>05</month>
<year>2016</year>
</pub-date>
<volume>11</volume>
<issue>12</issue>
<fpage>96</fpage>
<lpage>96</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 1997 The Author(s)</copyright-statement>
<copyright-year>1997</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This work is licensed under the <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</uri>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<related-article id="R1" related-article-type="commentary-article" ext-link-type="doi" xlink:href="10.1212/WNL.49.5.1389" vol="49" page="1389">
<article-title>Electroconvulsive therapy for treatment of intractable seizures. Initial findings in two children</article-title>
</related-article>
<abstract abstract-type="web-summary" specific-use="electronic-only">
<p>Two children aged 13 and 10 years with intractable epilepsy were treated with electroconvulsive therapy (ECT) for seizure control at the Children&#x2019;s Hospital, Charleston, SC.</p>
</abstract>
<kwd-group>
<kwd>Intractable Epilepsy</kwd>
<kwd>Electroconvulsive Therapy</kwd>
<kwd>Spontaneous Seizures</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p>Two children aged 13 and 10 years with intractable epilepsy were treated with electroconvulsive therapy (ECT) for seizure control at the Children&#x2019;s Hospital, Charleston, SC. A change in pattern but incomplete control of spontaneous seizures followed alternate-day ECT, and a series of 3 ECT seizures during a single session of anesthesia stopped spontaneous seizures and reduced the frequency of tonic seizures. ECT raised the ECT seizure threshold, was effective in ending nonconvulsive status, but benefits were transient and the value questionable. [<xref ref-type="bibr" rid="CIT0001">1</xref>]</p>
<p>COMMENT. Repeated electroshock seizures in laboratory animals results in an increase in the electroshock threshold and the necessity for a stronger current to induce a seizure. The rather barbaric nature of ECT and fear of causing further brain damage have probably deterred pediatric neurologists from using this method of treatment in children with refractory epilepsy, but the American Psychiatric Association condones its use in adults and psychiatrists have reported its efficacy since the 1940s. I am in agreement with the present authors who question whether ECT offers a reasonable option for treating intractable epilepsy in children, and other forms of medical or surgical therapy would seem preferable.</p>
</body>
<back>
<ref-list>
<ref id="CIT0001">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Griesemer</surname>
<given-names>DA</given-names>
</name>
<name>
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<given-names>CH</given-names>
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<given-names>MD</given-names>
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<given-names>GM</given-names>
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</person-group>
<article-title>Electroconvulsive therapy for treatment of intractable seizures. Initial findings in two children</article-title>
<source>Neurology</source>
<year>1997</year>
<month>Nov</month>
<volume>49</volume>
<issue>5</issue>
<fpage>1389</fpage>
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<pub-id pub-id-type="doi">10.1212/WNL.49.5.1389</pub-id>
<pub-id pub-id-type="pmid">9371927</pub-id>
</element-citation>
</ref>
</ref-list>
</back>
</article>