Teratogenic Effects of Antiepileptic Drugs

Authors

  • J Gordon Millichap Northwestern University Feinberg School of Medicine

DOI:

https://doi.org/10.15844/pedneurbriefs-11-10-14

Keywords:

Antiepileptic Drugs, Major Congenital Malformations, Polytherapy Exposures

Abstract

Data from 5 prospective European studies totaling 1,221 children exposed to antiepileptic drugs (AED) during pregnancy and 158 children of unexposed control pregnancies were analyzed to quantify the risk of major congenital malformations (MCM) and are reported from University Medical Centers in Rotterdam and Heemstede, The Netherlands; Berlin and Magdeburg, Germany; and Helsinki, Finland.

Published

1997-10-01

Issue

Section

Seizure Disorders